职 称：讲师

出生年月：1994年4月

专 业：分析化学

毕业院校：陕西师范大学

学历学位：博士/研究生

邮 箱：benkibio@snnu.edu.cn

研究方向：生化分析与分子诊断

研究内容：基于新型共轭聚合物纳米粒子的光热/光动力疗法，结合CRISPR基因编辑、PROTAC靶向蛋白降解、免疫微环境重塑以及氧化应激信号通路调控等多种技术开展了多角度、多层次的协同抗肿瘤治疗研究工作，显著增强了抗肿瘤治疗的效率。

已取得的科研成果：

[1]Benkai Bao, Qiong Yuan, Qian Feng, Ling Li, Meiqi Li, Yanli Tang* Regulating signal pathway brings circularly produced ROS for augmenting oxidative stress by enzyme-activated nanoparticles.CCS Chemistary, 2024, 6, 693-708. (SCI Ⅰ区Top, IF: 11.2)

[2]Benkai Bao, Ling Li, Meiqi Li, Yajie Long, Yanli Tang*Biomimeticcompositenanoparticles withimmunemodulation and CRISPRgeneediting forenhancingmildphotothermaltherapy-basedsynergisticantitumortherapy.Biomacromolecules. 2025,26, 8, 5245–5257. (SCI Ⅰ区, IF:5.4)

[3]Benkai Bao, Dong Gao, Ning Li, Manman Wu, and Chengfen Xing* Near-infrared light regulation of tumor PI3K/Akt signaling pathway for enhancing cancer cell apoptosis through conjugated polymer nanoparticles.ACS Applied Bio Materials. 2020, 3(4):2428-2437.(ESCI Ⅱ区，IF:4.7)

[4] Qiong Yuan,Benkai Bao,Meiqi Li,Yanli Tang* Bioactivecompositenanoparticles foreffectivemicroenvironmentregulation,neuroprotection, andcelldifferentiation.ACS Applied Materials & Interfaces. 2022, 14(13):15623–15631.(SCI Ⅱ区，IF:8.2)

[5] Qiong Yuan,Benkai Bao,Meiqi Li,Ling Li,Yanli Tang* Bioactive Conjugated Polymer-Based Biodegradable 3D Bionic Scaffolds for Facilitating Bone Defect Repair.Advanced Healthcare Materials. 2024,13(7):2428-2437.(SCIⅠ区，IF:9.6)

[6]包本开,杨佳娟,刘蕊.马拉硫磷降解菌株MN-13的降解性能测定及其培养基优化[J].河南农业科学, 2017, 46(09):88-91+97.(北大核心)